Detect critical organic contaminants with unamatched reliability, robustness, and accuracy in pharmaceutical Purified Water (PW) and Water for Injection (WFI) applications with the new Sievers M500 Online TOC Analyzer The Sievers M500 is our third generation online TOC analyzer for pharmaceutical grade water monitoring designed for accuracy, efficiency, and integrity. Building upon the proven results of the 500 RL, the M500 improves our industry-leading performance and adds a suite of cutting-edge features: Super iOS 4-port sampler automates grab samples to increase efficiency. Reducing analysis time by 50% facilitates utilization of real-time data, early detection, and process control. 10-inch touchscreen enables faster and easier setup and operation. Standardized and customized protocols improve productivity. Enhanced data features improve data integrity.
Detect critical organic contaminants with unamatched reliability, robustness, and accuracy in pharmaceutical Purified Water (PW) and Water for Injection (WFI) applications with the new Sievers M500 Online Analyzer
The Sievers M500 is our third generation online TOC analyzer for pharmaceutical grade water monitoring designed for accuracy, efficiency, and integrity. Building upon the proven results of the 500 RL, the M500 improves our industry-leading performance and adds a suite of cutting-edge features:
Super iOS 4-port sampler automates grab samples to increase efficiency.
Reducing analysis time by 50% facilitates utilization of real-time data, early detection, and process control.
10-inch touchscreen enables faster and easier setup and operation.
Standardized and customized protocols improve productivity.
Enhanced data features improve data integrity.
150% faster analysis time
Advanced communications: Ethernet, WiFi, 4-20mA, Modbus, and Serial connectivity
10-inch color touchscreen
Super iOS 4-port sampler automates grab samples to improve productivity
Simultaneous TOC & conductivity measurement
Automated system suitability calibration, & validation
50% faster validation protocols
IP55 & full IP connections
Same footprint as 500 RL for easy upgrades
The Sievers M500 leverages comprehensive industry-leading TOC data management tools to ensure data is secure. The Sievers M500 supports compliance to 21 CFR Part 11 and adherence to US FDA and other Pharmacopoeia Data Integrity guidelines using new data transfer, data security and data management features.
Data Transfer
Remote access using Ethernet and WiFi
Advanced communications using 4-20 mA, Modbus, and binary
Data Security
Password protection
Data encryption
Customizable access, roles, and permissions
Web-based Data Management
Closed system architecture
Customizable data transfer and export
Detect critical organic contaminants with unamatched reliability, robustness, and accuracy in pharmaceutical Purified Water (PW) and Water for Injection (WFI) applications with the new Sievers M500 Online Analyzer
The Sievers M500 is our third generation online TOC analyzer for pharmaceutical grade water monitoring designed for accuracy, efficiency, and integrity. Building upon the proven results of the 500 RL, the M500 improves our industry-leading performance and adds a suite of cutting-edge features:
Super iOS 4-port sampler automates grab samples to increase efficiency.
Reducing analysis time by 50% facilitates utilization of real-time data, early detection, and process control.
10-inch touchscreen enables faster and easier setup and operation.
Standardized and customized protocols improve productivity.
Enhanced data features improve data integrity.
150% faster analysis time
Advanced communications: Ethernet, WiFi, 4-20mA, Modbus, and Serial connectivity
10-inch color touchscreen
Super iOS 4-port sampler automates grab samples to improve productivity
Simultaneous TOC & conductivity measurement
Automated system suitability calibration, & validation
50% faster validation protocols
IP55 & full IP connections
Same footprint as 500 RL for easy upgrades
The Sievers M500 leverages comprehensive industry-leading TOC data management tools to ensure data is secure. The Sievers M500 supports compliance to 21 CFR Part 11 and adherence to US FDA and other Pharmacopoeia Data Integrity guidelines using new data transfer, data security and data management features.
Data Transfer
Remote access using Ethernet and WiFi
Advanced communications using 4-20 mA, Modbus, and binary
Data Security
Password protection
Data encryption
Customizable access, roles, and permissions
Web-based Data Management
Closed system architecture
Customizable data transfer and export
Total Organic Carbon | |
|---|---|
| Linear Range | 0.03 to 2,500 ppb as TOC |
| Accuracy | ± 5% of measurement; ±0.1 ppb |
| Precision | ± 1% of measurement; ±0.3 ppb |
| pH Range | 5.5 to 8.0 in order to meet accuracy specification |
| Analysis Modes | On-line, on-line averaged, on-line timed, Grab |
| Analysis Time1,2 | 3 minutes for continuous online measurements |
| Ozone Compatibility | 50 ppb O3 continuous; 200 ppb 03 for 2 hours daily |
| External Flow Rate | Minimum 50 mL/min |
| Sample Temperature | 1–95 °C (34–203 °F) (withstands short-term exposure) |
| Sample Pressure | Up to 100 psig |
| Interferences | Insensitive to organic heteroatoms |
| Calibration Stability | Typically stable for 12 months |
| Display Readout | 3 significant digits |
Conductivity | |
| Raw Conductivity Range | 0.01 to 800 µS/cm |
| Conductivity Accuracy | 0.005 µS/cm or 1%, whichever is greater |
| Conductivity Precision | <1.0% RSD |
Instrument | |
| Power Requirements | 100–240 VAC, 70 W, 50/60 Hz |
| Fuses | No user-replaceable fuses |
| Normal Operating Environment | Intended for indoor use only |
| Ambient Temperature | 5–40°C (41–104°F) |
| Maximum Relative Humidity | Up to 95%, noncondensing |
| Maximum Altitude | 3,000 m (9,843 ft) |
| Inputs | Two isolated binary inputs |
| Outputs | Serial (RS-232), one USB, three 40-20 mA, four alarms, one Ethernet |
| Installation/Overvoltage | II (protects against transients present in Category II power) |
| Safety Certifications | CE, ETL listed. Conforms to UL Std. 61010-1. Certified to CSA 22.2 No. 61010-1. |
| Pollution Degree | 2 (normally only non-conductive pollution) |
| Display | Backlit 10.1", 1280x800, touchscreen display |
| Size | H: 43.4 cm (17.1 in); W: 55.9 cm (22.0 in); D: 28.7 cm (11.3 in) |
| Weight | 16.3 kg (36 lb) |
| IP Rating | IP 55 |
| Optional Wi-Fi | 802.11ac/a/b/g/n Dual-band 2.4/5 GHz |
| Industrial Communications Protocol | Modbus TCP/IP |
1Time to first measurement is 10 minutes
2Base model analysis time is six minutes for continuous online measurement
